关键词: SUDEP atrial fibrillation central autonomic network epilepsy epileptic seizure

Mesh : Death, Sudden / etiology Electrocardiography / methods Electroencephalography / methods Epilepsy / complications therapy Humans Male Middle Aged Seizures / complications diagnosis therapy Treatment Outcome

来  源:   DOI:10.1684/epd.2019.1070

Abstract:
Cardiac arrhythmias are a common but often overlooked symptom that occur during or after epileptic seizures. The characterization of seizure-related heart rhythm disorders could shed light on the functional organization of the so-called \"central autonomic network\" and possibly on the pathophysiology of sudden death of epilepsy patients (SUDEP). Indeed, epileptic discharges may affect the heart through the involvement of cortical regions selectively driving autonomic functions. Ictal atrial fibrillation is an exceedingly rare phenomenon, usually associated with generalized tonic-clonic seizures. Here, we report a case of paroxysmal atrial fibrillation as a core presenting feature of a focal non-motor seizure in a 68-year-old man, at first misdiagnosed and treated for a typical cardiogenic arrhythmia. A brief literature review is included.
摘要:
心律失常是在癫痫发作期间或之后发生的常见但经常被忽视的症状。癫痫相关的心律紊乱的表征可以揭示所谓的“中枢自主神经网络”的功能组织,并可能揭示癫痫患者猝死(SUDEP)的病理生理学。的确,癫痫性放电可能通过累及皮质区域选择性地驱动自主神经功能而影响心脏。心房颤动是一种极其罕见的现象,通常与全身性强直-阵挛性癫痫发作有关。这里,我们报告了一例阵发性心房颤动作为局灶性非运动性癫痫发作的核心特征的68岁男性,最初误诊为典型的心源性心律失常。包括简短的文献综述。
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