使用 Crispr CAS9 对肺癌的可翻译基因治疗 - 一项探索性综述。
Mesh : Animals Biomarkers, Tumor / genetics CRISPR-Cas Systems / genetics Carcinoma, Non-Small-Cell Lung / diagnosis genetics therapy Cell Line, Tumor Chromosomes, Human, Pair 3 / genetics Chromosomes, Human, Pair 5 / genetics Chromosomes, Human, Pair 9 / genetics Clinical Trials as Topic Gene Editing / methods Gene Knockout Techniques Genetic Therapy / methods Humans Lung Neoplasms / diagnosis genetics therapy Mice Mutation Sequence Deletion Translational Research, Biomedical / methods Tumor Suppressor Proteins / genetics
来 源: DOI:10.1038/s41417-019-0116-8 PDF(Sci-hub)