Toxoplasmosis Seroprevalence in Romanian Children.

• 影响指数: 2.523
• 发表时间: 11 2019
• 来源期刊: Vector Borne Zoonotic Dis
• DOI: 10.1089/vbz.2018.2435
• PMID: 31216238
• 文章类型: Journal Article
• 中科院分区: Q4
• 方向: 医学
• 作者列表: Căpraru ID,Lupu MA,Horhat F,Olariu TR

关键词: Toxoplasma gondii; Western Romania; children; seroprevalence; toxoplasmosis

Mesh: Adolescent; Antibodies, Protozoan / blood; Child; Child, Preschool; Female; Humans; Immunoglobulin G / blood; Immunoglobulin M / blood; Infant; Male; Romania / epidemiology; Rural Population; Seroepidemiologic Studies; Toxoplasma / immunology; Toxoplasmosis / epidemiology; Urban Population

Abstract

The seroprevalence of Toxoplasma gondii in Romanian children is currently unknown. A serological survey was undertaken to determine T. gondii infection among children from Western Romania. Serum samples of 441 children (aged 1-18 years) were screened for T. gondii immunoglobulin G and immunoglobulin M antibodies. The overall T. gondii seroprevalence was 16.6% and tended to increase with age. Seroprevalence was 18.4% in children from rural regions and 14.7% in those from urban regions. T. gondii antibodies were demonstrated in 19.5% of females and 13.3% of males. This report provided the first seroepidemiological data and evaluated the demographic risk factors regarding T. gondii infection in children from Western Romania. Our results may serve as a basis for a future prevention program for toxoplasmosis.