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Abstract：
Although most patients with acute pancreatitis have the mild form of the disease, about 20-30% develops a severe form, often associated with single or multiple organ dysfunction requiring intensive care. Identifying the severe form early is one of the major challenges in managing severe acute pancreatitis. Infection of the pancreatic and peripancreatic necrosis occurs in about 20-40% of patients with severe acute pancreatitis, and is associated with worsening organ dysfunctions. While most patients with sterile necrosis can be managed nonoperatively, patients with infected necrosis usually require an intervention that can be percutaneous, endoscopic, or open surgical. These guidelines present evidence-based international consensus statements on the management of severe acute pancreatitis from collaboration of a panel of experts meeting during the World Congress of Emergency Surgery in June 27-30, 2018 in Bertinoro, Italy. The main topics of these guidelines fall under the following topics: Diagnosis, Antibiotic treatment, Management in the Intensive Care Unit, Surgical and operative management, and Open abdomen.
摘要：
尽管大多数急性胰腺炎患者患有轻度疾病，大约20-30%的人发展成严重的形式，通常与需要重症监护的单个或多个器官功能障碍有关。早期识别严重形式是管理严重急性胰腺炎的主要挑战之一。大约20-40％的重症急性胰腺炎患者发生胰腺和胰周坏死的感染，并与器官功能障碍恶化有关。虽然大多数无菌坏死患者可以非手术治疗，感染坏死的患者通常需要经皮干预，内窥镜,或开腹手术.这些指南提出了基于证据的关于重症急性胰腺炎管理的国际共识声明，来自2018年6月27日至30日在Bertinoro举行的世界急诊外科大会期间的专家小组会议的合作。意大利。这些指南的主要主题属于以下主题：诊断，抗生素治疗,重症监护病房的管理，外科和手术管理，打开腹部。
