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Abstract：
BACKGROUND: Scalp mycosis is often caused by dermatophytes and was so called tinea capitis. There is no published report caused by Aspergillus protuberus. We report a rare case of kerion-type scalp mycosis caused by A. protuberus.
METHODS: A 5-year-old girl developed pyogenic mass with pain for 8 days and got a fever for 2 days prior to admission. Surgical incision and drainage of the mass, intravenous cefuroxime and metronidazole in the local hospital aggravated the skin lesions. Species identification was performed by observation of morphologic and biochemical characteristicsand sequencing of the internal transcribed spacer (ITS) and β-tubulin (BT2). Treatment with oral and topical antifungal agents was effective with no relapse during the six months of clinical follow-up.
CONCLUSIONS: Aspergillusis a opportunistic pathogenic fungus and its infection occurs mostly in patients with underlying conditions and immunocompromised statuses. So far no report of kerion-type scalp infection has been reported. The first case of kerion-type scalp mycosis caused by A. protuberus was described to highlight the importance of mycological examination that helps to recognize rare pathogenic fungi. Any boggy lesion with hair loss over the scalp and non-responsive to antibiotics should be suspected as resulting from fungal infection, and mycological examination should be performed, especially in children.
METHODS: A 5-year-old girl developed pyogenic mass with pain for 8 days and got a fever for 2 days prior to admission. Surgical incision and drainage of the mass, intravenous cefuroxime and metronidazole in the local hospital aggravated the skin lesions. Species identification was performed by observation of morphologic and biochemical characteristicsand sequencing of the internal transcribed spacer (ITS) and β-tubulin (BT2). Treatment with oral and topical antifungal agents was effective with no relapse during the six months of clinical follow-up.
CONCLUSIONS: Aspergillusis a opportunistic pathogenic fungus and its infection occurs mostly in patients with underlying conditions and immunocompromised statuses. So far no report of kerion-type scalp infection has been reported. The first case of kerion-type scalp mycosis caused by A. protuberus was described to highlight the importance of mycological examination that helps to recognize rare pathogenic fungi. Any boggy lesion with hair loss over the scalp and non-responsive to antibiotics should be suspected as resulting from fungal infection, and mycological examination should be performed, especially in children.
摘要：
背景：头皮真菌病通常由皮肤癣菌引起，被称为头癣。目前尚无发表的由隆曲霉引起的报道。我们报告了一例罕见的由突起A引起的角离子型头皮真菌病。
方法：一名5岁女孩在入院前出现化脓性肿块，疼痛持续8天，发烧2天。肿块的手术切口和引流，在当地医院静脉注射头孢呋辛和甲硝唑加重了皮肤病变。物种鉴定是通过观察内部转录间隔区（ITS）和β-微管蛋白（BT2）的形态和生化特征以及测序进行的。口服和局部抗真菌药物治疗有效，在临床随访的六个月中没有复发。
结论：曲霉属机会致病性真菌，其感染主要发生在有潜在疾病和免疫功能低下状态的患者中。到目前为止，还没有关于角质型头皮感染的报道。描述了第一例由突起A引起的角质型头皮真菌病，以强调真菌学检查的重要性，该检查有助于识别罕见的病原真菌。任何头皮上脱发且对抗生素无反应的沼泽性病变应怀疑是由真菌感染引起的，应该进行真菌学检查，尤其是儿童。
方法：一名5岁女孩在入院前出现化脓性肿块，疼痛持续8天，发烧2天。肿块的手术切口和引流，在当地医院静脉注射头孢呋辛和甲硝唑加重了皮肤病变。物种鉴定是通过观察内部转录间隔区（ITS）和β-微管蛋白（BT2）的形态和生化特征以及测序进行的。口服和局部抗真菌药物治疗有效，在临床随访的六个月中没有复发。
结论：曲霉属机会致病性真菌，其感染主要发生在有潜在疾病和免疫功能低下状态的患者中。到目前为止，还没有关于角质型头皮感染的报道。描述了第一例由突起A引起的角质型头皮真菌病，以强调真菌学检查的重要性，该检查有助于识别罕见的病原真菌。任何头皮上脱发且对抗生素无反应的沼泽性病变应怀疑是由真菌感染引起的，应该进行真菌学检查，尤其是儿童。
