Abstract:
Vestibular neuritis (VN) can affect utricular afferents. Utricular function can be assessed by ocular vestibular evoked myogenic potentials (oVEMPs) whose abnormalities include weak or absent responses, and ocular cycloposition whose abnormalities include ocular torsion (OT). When studied independently in vestibular neuritis, oVEMPs are abnormal in 61-82% of cases, and OT is present in 72-80% of cases. The similar range of abnormalities suggests the hypothesis that these tests should be concordantly abnormal. We tested this hypothesis by identifying consecutive adult cases of VN in whom both oVEMPs and OT were performed. OT and oVEMP overlapped (both were abnormal) in only 47% of cases. In 40% of cases oVEMPs alone were abnormal, and in 13% of cases, OT alone was present. These results suggest that oVEMPs and OT assess different aspects of utricular function believed to arise from discrete zones of the utricular macula; the former are thought to reflect the activity of extra-striolar afferents (which detect constant acceleration), and the latter reflects the activity of striolar afferents (which detect change in acceleration).
摘要:
前庭神经炎(VN)可影响泪腺传入。可以通过眼前庭诱发的肌源性电位(oVEMPs)评估尿功能,其异常包括弱或无反应。和异常包括眼扭转(OT)的眼摆位。当在前庭神经炎中独立研究时,oVEMPs在61-82%的病例中异常,在72-80%的病例中存在OT。相似范围的异常表明这些测试应该是一致异常的假设。我们通过确定同时进行oVEMPs和OT的VN连续成人病例来检验这一假设。OT和oVEMP重叠(均异常)的病例只有47%。在40%的病例中,OVEMPs是异常的,在13%的案例中,只有OT在场。这些结果表明,oVEMPs和OT评估了被认为是由黄斑的离散区域引起的眼肌功能的不同方面;前者被认为反映了纹状体外传入的活动(检测到恒定的加速度),后者反映了纹状体传入的活动(检测加速度的变化)。