METHODS: A systematic literature review was conducted to identify the incidence and prevalence of sVMA based on international epidemiologic studies, weighted for study size and then averaged across eligible studies. A second systematic review aimed to estimate the proportion of vitrectomy undertaken for sVMA in Germany. This was combined with the reported number of vitrectomies in Germany in 2016 to estimate the number of patients undergoing vitrectomy for sVMA.
RESULTS: The prevalence of sVMA is 1,365 per 100,000 population, with an incidence of 6.96 per 100,000 per year. For Germany, this translates to 1,119,300 cases, with 5,700 new cases reported annually. Analyzing the national hospital statistics, ~2,300 patients undergo vitrectomy due to sVMA in Germany each year, of which about 1,700 patients have VMT.
CONCLUSIONS: Incidence figures, driven by patients presenting to clinic, are much lower than expected based on population-based studies, suggesting that many patients with sVMA exist outside of the clinic system.
方法:根据国际流行病学研究,进行了系统的文献综述,以确定sVMA的发病率和患病率。对研究规模进行加权,然后在符合条件的研究中进行平均。第二次系统评价旨在评估德国sVMA的玻璃体切除术比例。这与2016年德国报道的玻璃体切除术数量相结合,以估计接受sVMA玻璃体切除术的患者人数。
结果:sVMA的患病率为每100,000人口1,365,发病率为每年6.96/100,000。对于德国来说,这相当于1,119,300例,每年报告5700例新病例。分析全国医院统计数据,在德国,每年约有2,300例患者因sVMA而接受玻璃体切除术,其中约1,700名患者患有VMT。
结论:发病率数字,在患者出现在诊所的驱使下,远低于基于人群的研究的预期,这表明许多sVMA患者存在于临床系统之外。