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Abstract：
Adults with solid brain metastases who have not experienced a seizure.
Do prophylactic antiepileptic drugs (AEDs) decrease the risk of seizures in nonsurgical patients with brain metastases who are otherwise seizure-free?
Level 3: Prophylactic AEDs are not recommended for patients with brain metastases who did not undergo surgical resection and are otherwise seizure-free.
Do prophylactic AEDs decrease the risk of seizures in patients with brain metastases and no prior history of seizures in the postoperative setting?
Level 3: Routine postcraniotomy AED use for seizure-free patients with brain metastases is not recommended.The full guideline can be found at: https://www.cns.org/guidelines/guidelines-treatment-adults-metastatic-brain-tumors/chapter_8.
Do prophylactic antiepileptic drugs (AEDs) decrease the risk of seizures in nonsurgical patients with brain metastases who are otherwise seizure-free?
Level 3: Prophylactic AEDs are not recommended for patients with brain metastases who did not undergo surgical resection and are otherwise seizure-free.
Do prophylactic AEDs decrease the risk of seizures in patients with brain metastases and no prior history of seizures in the postoperative setting?
Level 3: Routine postcraniotomy AED use for seizure-free patients with brain metastases is not recommended.The full guideline can be found at: https://www.cns.org/guidelines/guidelines-treatment-adults-metastatic-brain-tumors/chapter_8.
摘要：
患有实质性脑转移的成年人，没有经历过癫痫发作。
预防性抗癫痫药物（AEDs）是否能降低非手术性脑转移患者的癫痫发作风险？
第3级：对于未接受手术切除且无癫痫发作的脑转移患者，不推荐预防性AEDs。
预防性AED是否可以降低术后无癫痫发作史的脑转移患者的癫痫发作风险？
第3级：对于无癫痫发作的脑转移患者，不建议常规开颅手术后使用AED。完整的指南可以在：https://www上找到。cns.org/指南/指南-治疗-成人-转移性-脑肿瘤/chapter_8.
预防性抗癫痫药物（AEDs）是否能降低非手术性脑转移患者的癫痫发作风险？
第3级：对于未接受手术切除且无癫痫发作的脑转移患者，不推荐预防性AEDs。
预防性AED是否可以降低术后无癫痫发作史的脑转移患者的癫痫发作风险？
第3级：对于无癫痫发作的脑转移患者，不建议常规开颅手术后使用AED。完整的指南可以在：https://www上找到。cns.org/指南/指南-治疗-成人-转移性-脑肿瘤/chapter_8.
