{Reference Type}: Journal Article
{Title}: Congress of Neurological Surgeons Systematic Review and Evidence-Based Guidelines on the Role of Prophylactic Anticonvulsants in the Treatment of Adults with Metastatic Brain Tumors.
{Author}: Chen CC;Rennert RC;Olson JJ;
{Journal}: Neurosurgery
{Volume}: 84
{Issue}: 3
{Year}: 03 2019 1
{Factor}: 5.315
{DOI}: 10.1093/neuros/nyy545
{Abstract}: Adults with solid brain metastases who have not experienced a seizure.<BR>Do prophylactic antiepileptic drugs (AEDs) decrease the risk of seizures in nonsurgical patients with brain metastases who are otherwise seizure-free?<BR>Level 3: Prophylactic AEDs are not recommended for patients with brain metastases who did not undergo surgical resection and are otherwise seizure-free.<BR>Do prophylactic AEDs decrease the risk of seizures in patients with brain metastases and no prior history of seizures in the postoperative setting?<BR>Level 3: Routine postcraniotomy AED use for seizure-free patients with brain metastases is not recommended.The full guideline can be found at: https://www.cns.org/guidelines/guidelines-treatment-adults-metastatic-brain-tumors/chapter_8.