关键词: Anaphylaxis FDEIA augmentation co-factors diagnosis exercise exercise induced anaphylaxis food allergy food dependent exercise induced anaphylaxis management

Mesh : Anaphylaxis / etiology physiopathology therapy Exercise / physiology Food Hypersensitivity / complications physiopathology therapy Humans

来  源:   DOI:10.1080/1744666X.2019.1562904   PDF(Sci-hub)

Abstract:
Exercise-induced anaphylaxis (EIA) denotes a range of disorders where anaphylaxis occurs in relation to physical exercise. Typical symptoms include flushing, pruritus, urticaria, angioedema, respiratory symptoms, gastrointestinal symptoms, hypotension, and collapse during or after exercise. The far best described entity within EIA is food-dependent exercise-induced anaphylaxis (FDEIA), where symptoms only occur in combination with food intake. Frequency and predictability of symptoms vary, and some patients experience symptoms only if exercise is accompanied by other co-factors Areas covered: In the present review, we aimed to provide an overview of EIA, diagnostic workup, causes, management and discuss areas in need of further research. Expert opinion: Though rare, EIA is an entity that all allergists and practicing physicians should recognize. The pathophysiological and immunological mechanisms of EIA are largely unknown. Management is centered upon avoidance of eliciting factors, where emergency plans are individualized, except a mandatory prescription of an adrenaline auto-injector.
摘要:
运动诱发的过敏反应(EIA)表示一系列与体育锻炼有关的过敏反应发生的疾病。典型的症状包括潮红,瘙痒,荨麻疹,血管性水肿,呼吸道症状,胃肠道症状,低血压,在运动期间或运动后崩溃。EIA中描述得最好的实体是食物依赖性运动诱发的过敏反应(FDEIA),其中症状仅与食物摄入结合发生。症状的频率和可预测性各不相同,一些患者只有在运动伴随着其他共同因素时才会出现症状:在本综述中,我们旨在提供环境影响评估的概述,诊断检查,原因,管理和讨论需要进一步研究的领域。专家意见:虽然罕见,EIA是所有过敏症专家和执业医师都应该认识的实体。EIA的病理生理学和免疫学机制在很大程度上是未知的。管理的中心是避免引发因素,应急计划是个性化的,除了肾上腺素自动注射器的强制性处方.
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