用于产生含有人样 O - 连接聚糖的治疗性蛋白质的细菌表达平台。
关键词: T antigen glycosylation human growth hormone interferon-α2b operon
Mesh : Bacterial Proteins / genetics metabolism Campylobacter jejuni / enzymology Escherichia coli / metabolism Galactosyltransferases / genetics metabolism Glycosylation Growth Hormone / genetics metabolism Humans Interferon alpha-2 / genetics metabolism N-Acetylgalactosaminyltransferases / genetics metabolism Polysaccharides / metabolism Protein Disulfide-Isomerases / genetics metabolism Recombinant Proteins / biosynthesis isolation & purification UDPglucose 4-Epimerase / genetics metabolism Polypeptide N-acetylgalactosaminyltransferase
来 源:
DOI:10.1016/j.chembiol.2018.10.017
PDF(Sci-hub)