Hepatosplenic T-Cell Lymphoma in an Immunocompetent Male with Central Nervous System Invasion: A Rare Clinical Entity.

• 影响指数: 3.248
• 发表时间: 11 2019
• 来源期刊: Cytometry B Clin Cytom
• DOI: 10.1002/cyto.b.21736
• PMID: 30500103
• 文章类型: Case Reports
• 中科院分区: Q3
• 方向: 医学
• 作者列表: Wu F,Pan Y,Wang H,Tao Q,An F,Zhang J,Zhai Z

关键词: flow cytometry; hepatosplenic T-cell lymphoma; hepatosplenomegaly; immunophenotyping

Mesh: Central Nervous System Neoplasms / diagnosis immunology secondary; Flow Cytometry; Humans; Liver Neoplasms / diagnosis immunology; Lymphoma, T-Cell / diagnosis immunology; Male; Middle Aged; Optical Imaging; Splenic Neoplasms / diagnosis immunology

Abstract

Hepatosplenic T-cell lymphoma (HSTCL) is a very rare non-Hodgkin lymphoma with an aggressive clinical course and poor prognosis. Patients of this disease usually presented with hepatosplenomegaly, which can be misdiagnosed or delayed. Bone marrow (BM) and peripheral blood (PB) are frequently involved, however, central nervous system (CNS) involvement is less common. Here, we are reporting an unusual case of hepatosplenic γδ T-cell lymphoma in a 64-year-old man with CNS involvement. Flow cytometry immunophenotyping was proved of great diagnostic contribution. © 2018 International Clinical Cytometry Society.