关键词： acute periprosthetic joint infection (PJI) antibiotic combination antibiotic duration antibiotic therapy antibiotic treatment biofilm chronic obstructive pulmonary disease (COPD)), and C-reactive protein (CRP) >115 mg/L (C), rheumatoid arthritis (R), indication prosthesis (I), male (M), exchange of mobile components (E), age > 80 years (80) (CRIME80) scores chronic renal failure (K), liver cirrhosis (L), index surgery (I), cemented prosthesis (C), and C-reactive protein (CRP) >115 mg/L (KLIC) score contraindications debridement antibiotics and retention of the prosthesis debridement, antibiotics, implant retention (DAIR) emergency management exchange of modular components failed debridement, antibiotics, implant retention (DAIR) management fluoroquinolone gram-negative acute periprosthetic joint infection (PJI) indications infection recurrence intra-articular antibiotic infusion irrigation irrigation and debridement irrigation solution length of antibiotics megaprosthesis methicillin-resistant Staphylococcus aureus (MRSA) pathogen identification patient optimization periprosthetic joint infection (PJI) recurrence povidone-iodine rifampicin risk stratification surgical factors surgical intervention surgical outcome surgical outcomes surgical site infection (SSI) recurrence surgical timing treatment failure treatment success two-stage exchange arthroplasty unicompartmental knee arthroplasty debridement, antibiotics, implant retention (DAIR)

来  源：   DOI：10.1016/j.arth.2018.09.025   PDF(Sci-hub)

Abstract：
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