PDF(Pubmed)
Abstract：
Risk for suicidal behavior may fluctuate across the menstrual cycle. Here, we use the RDoC framework to review potential mechanisms by which the cycle may increase acute suicide risk.
The menstrual cycle impacts the majority of RDoC constructs linked to suicide risk, particularly among hormone-sensitive women, such as those with premenstrual dysphoric disorder or premenstrual exacerbation of a psychiatric disorder. Despite this, there are no published studies examining suicidal ideation, planning, or behavior longitudinally across the cycle. More work is needed to understand how hormone sensitivity may relate to both trait and state suicide risk. Intensive multilevel investigations of cyclical hormone effects on suicide risk through specific RDoC mechanisms are suggested. This is a fertile research area and may provide key insights regarding the mechanisms of acute suicide risk.
The menstrual cycle impacts the majority of RDoC constructs linked to suicide risk, particularly among hormone-sensitive women, such as those with premenstrual dysphoric disorder or premenstrual exacerbation of a psychiatric disorder. Despite this, there are no published studies examining suicidal ideation, planning, or behavior longitudinally across the cycle. More work is needed to understand how hormone sensitivity may relate to both trait and state suicide risk. Intensive multilevel investigations of cyclical hormone effects on suicide risk through specific RDoC mechanisms are suggested. This is a fertile research area and may provide key insights regarding the mechanisms of acute suicide risk.
摘要：
自杀行为的风险可能在整个月经周期中波动。这里,我们使用RDoC框架审查了该周期可能增加急性自杀风险的潜在机制.
月经周期影响大多数与自杀风险相关的RDoC结构，尤其是对激素敏感的女性，如患有经前烦躁不安症或精神病的经前恶化者。尽管如此,没有发表的研究检查自杀意念，规划,或在整个周期中纵向的行为。需要更多的工作来了解激素敏感性如何与特质和状态自杀风险有关。建议通过特定的RDoC机制对周期性激素对自杀风险的影响进行深入的多水平调查。这是一个肥沃的研究领域，可能提供有关急性自杀风险机制的关键见解。
月经周期影响大多数与自杀风险相关的RDoC结构，尤其是对激素敏感的女性，如患有经前烦躁不安症或精神病的经前恶化者。尽管如此,没有发表的研究检查自杀意念，规划,或在整个周期中纵向的行为。需要更多的工作来了解激素敏感性如何与特质和状态自杀风险有关。建议通过特定的RDoC机制对周期性激素对自杀风险的影响进行深入的多水平调查。这是一个肥沃的研究领域，可能提供有关急性自杀风险机制的关键见解。
