关键词: coexisting fetus complete hydatidiform mole gestational trophoblastic neoplasia magnetic resonance imaging (MRI)

Mesh : Abortion, Therapeutic Adult Chorionic Gonadotropin, beta Subunit, Human / blood Female Humans Hydatidiform Mole / diagnostic imaging surgery Magnetic Resonance Imaging Placenta / diagnostic imaging Pregnancy Pregnancy, Twin Twins Ultrasonography, Prenatal Uterine Neoplasms / diagnostic imaging surgery Young Adult

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Abstract:
BACKGROUND: Both twin pregnancies with complete hydatidiform mole and coexisting normal fetus (CHMCF) and partial hydatidiform mole can be found in association with a live fetus and a placenta displaying a molar degeneration. Two cases of CHMCF using magnetic resonance imaging (MRI) for a diagnosis are reported.
METHODS: In the first, CHMCF was suspected at 12 weeks of gestation. At 18 weeks of gestation, the existence of molar placenta and a sac separating from fetus and normal placenta was clearly depicted on MRI. At 19 weeks of gestations, she had termination of pregnancy because of a development of gestational trophoblastic neoplasia (GTN) and started chemotherapy. In the second case, CHMCF was suspected at 14 weeks of gestation. MRI demonstrated the existence of molar placenta and a sac separating from fetus and normal placenta. She chose induced abortion and there was no evidence of GTN during the 1 year-follow up period. Pathological examination in both cases was consistent with a complete hydration mole and a coexisting normal female fetus.
CONCLUSIONS: MRI was useful for an accurate diagnosis for CHMCF.
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