关键词: Acuité visuelle Diabète de type 2 HbA1c Insulin Insuline Papilledema Type 2 diabetes mellitus Visual acuity Œdème papillaire

Mesh : Aged Diabetes Mellitus, Type 2 / complications diagnosis drug therapy Diabetic Retinopathy / chemically induced diagnosis Dose-Response Relationship, Drug Female Fluorescein Angiography Humans Insulin / administration & dosage adverse effects Papilledema / chemically induced diagnosis Visual Acuity / drug effects

来  源:   DOI:10.1016/j.revmed.2018.08.007

Abstract:
BACKGROUND: Diabetic papillopathy is a rare ocular complication of diabetes. Its pathophysiology is not well known. It is a unilateral or bilateral optic disc edema with variable degrees of visual loss.
METHODS: A 66-year-old woman, with a twelve years old type 2 diabetes mellitus, suddenly presented a unilateral decreased vision. Her ocular examination was normal eight months earlier. Ocular examination, radiological investigations and laboratory analysis were conclusive of diabetic papillopathy. Medical history revealed a recent rapid improvement of blood glucose control after intensification of insulin therapy. A visual acuity improvement with spontaneous regression of papillary edema was observed.
CONCLUSIONS: There is a risk of diabetic papillopathy associated with the rapid control of blood glucose levels after intensification of insulin therapy, even in diabetic patients without known retinopathy.
摘要:
背景:糖尿病性乳头病是一种罕见的糖尿病眼部并发症。其病理生理学尚不为人所知。它是单侧或双侧视盘水肿,伴有不同程度的视力丧失。
方法:一个66岁的女人,患有12岁的2型糖尿病,突然出现单侧视力下降。八个月前她的眼部检查正常。眼部检查,放射学检查和实验室分析是糖尿病性乳头状病变的结论。病史显示,强化胰岛素治疗后血糖控制最近迅速改善。观察到视敏度改善,乳头状水肿自发消退。
结论:强化胰岛素治疗后血糖水平的快速控制存在糖尿病性乳头病的风险,甚至在没有已知视网膜病变的糖尿病患者中。
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