Abstract:
Nasopharyngeal carcinoma is a rare condition, with less than 300 cases occurring per year in France. Its treatment can be difficult due to the importance of side effects, but tumor control is usually excellent following a well conducted chemoradiotherapy. This article summarizes the recent advances in nasopharyngeal cancer diagnosis, classification, treatment, surveillance and management of recurrences. Chemotherapy timing is discussed, along with arguments in favor of induction chemotherapy in locally advanced cases. As a survival advantage has been suggested for when patients are treated in high volume center it seems reasonable to refer these young patients for treatment to tertiary expert centers, especially given the low incidence of the disease.
摘要:
鼻咽癌是一种罕见的疾病,法国每年发生的病例不到300例。由于副作用的重要性,它的治疗可能很困难,但是在进行良好的放化疗后,肿瘤控制通常是极好的。本文综述了近年来鼻咽癌诊断的研究进展,分类,治疗,复发的监测和管理。讨论了化疗时机,以及支持局部晚期病例诱导化疗的论点。作为生存优势已被提出,当患者在高容量中心治疗时,似乎合理的将这些年轻患者转诊到三级专家中心治疗。特别是考虑到这种疾病的发病率低。