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Abstract：
Hypervirulent Klebsiella pneumoniae strains have higher potential to cause more severe and disseminated infections than classic K. pneumoniae strains. While initially reported from East Asian countries, cases have now been identified worldwide, sometimes in conjunction with extensive drug resistance. In this issue of the Journal of Clinical Microbiology, T. A. Russo et al. (J Clin Microbiol 56:e00776-18, 2018, https://doi.org/10.1128/JCM.00776-18) validated the diagnostic accuracy of biomarkers that differentiate hypervirulent K. pneumoniae strains from classic strains. This represents a major step forward in building a consensus definition and designing international studies aimed at elucidating the global epidemiology, clinical features, and outcome of this important pathogen.
摘要：
与经典肺炎克雷伯菌菌株相比，高毒力肺炎克雷伯菌菌株具有更高的可能引起更严重和传播的感染。虽然最初来自东亚国家，现在已经在世界范围内发现了病例，有时与广泛的耐药性有关。在本期《临床微生物学杂志》上，T.A.Russo等人。（JClinMicrobiol56：e00776-18，2018，https://doi.org/10.1128/JCM.00776-18）验证了区分高毒力肺炎克雷伯菌菌株与经典菌株的生物标志物的诊断准确性。这是在建立共识定义和设计旨在阐明全球流行病学的国际研究方面迈出的重要一步。临床特征,以及这种重要病原体的结果。
