Abstract：
Inhaled racemic adrenaline was used for bronchiolitis in many hospitals in Finland prior to new national current care guidelines for bronchiolitis in 2014, which limited its recommendations to on-demand rescue therapy. We studied the drug\'s use before and after the new guidelines to gauge changes in prescribing habits.
This 2012-2016 study analysed how many 0.5 mL doses of racemic adrenaline were used for children by emergency rooms, paediatric wards and paediatric intensive care units at four university hospitals and estimated drug and staff costs.
There were substantial differences in the yearly consumption of racemic adrenaline between the hospitals before and after the bronchiolitis guidelines were published, with reductions in drug costs and staff time. The overall use more than halved during the study period, particularly in two hospitals where baseline consumptions were highest, but not in a third where baseline consumption was already low. In the fourth, the baseline consumption was modest and there was a constant decrease during the study years.
The current care guidelines for bronchiolitis had some impact on clinical practice, as the overall use of racemic adrenaline more than halved, but considerable differences remained in the four study hospitals after their publication.
This 2012-2016 study analysed how many 0.5 mL doses of racemic adrenaline were used for children by emergency rooms, paediatric wards and paediatric intensive care units at four university hospitals and estimated drug and staff costs.
There were substantial differences in the yearly consumption of racemic adrenaline between the hospitals before and after the bronchiolitis guidelines were published, with reductions in drug costs and staff time. The overall use more than halved during the study period, particularly in two hospitals where baseline consumptions were highest, but not in a third where baseline consumption was already low. In the fourth, the baseline consumption was modest and there was a constant decrease during the study years.
The current care guidelines for bronchiolitis had some impact on clinical practice, as the overall use of racemic adrenaline more than halved, but considerable differences remained in the four study hospitals after their publication.
摘要：
在2014年新的国家现行细支气管炎护理指南之前，芬兰许多医院都使用了吸入外消旋肾上腺素治疗细支气管炎，该指南将其建议限制为按需抢救治疗。我们研究了该药物在新指南前后的使用情况，以评估处方习惯的变化。
这项2012-2016年的研究分析了急诊室对儿童使用了多少剂量的外消旋肾上腺素。四所大学医院的儿科病房和儿科重症监护室，以及估计的药物和员工成本。
在细支气管炎指南公布之前和之后，各医院的外消旋肾上腺素的年消费量存在显著差异。减少药物成本和员工时间。在研究期间，总体使用量减少了一半以上，特别是在基线消费最高的两家医院，但不是在三分之一的基线消费已经很低。在第四,基线消耗量适中,且在研究期间持续下降.
目前的毛细支气管炎护理指南对临床实践产生了一些影响，因为外消旋肾上腺素的总体使用量减少了一半以上，但四家研究医院在发表后仍存在相当大的差异.
这项2012-2016年的研究分析了急诊室对儿童使用了多少剂量的外消旋肾上腺素。四所大学医院的儿科病房和儿科重症监护室，以及估计的药物和员工成本。
在细支气管炎指南公布之前和之后，各医院的外消旋肾上腺素的年消费量存在显著差异。减少药物成本和员工时间。在研究期间，总体使用量减少了一半以上，特别是在基线消费最高的两家医院，但不是在三分之一的基线消费已经很低。在第四,基线消耗量适中,且在研究期间持续下降.
目前的毛细支气管炎护理指南对临床实践产生了一些影响，因为外消旋肾上腺素的总体使用量减少了一半以上，但四家研究医院在发表后仍存在相当大的差异.
