关键词: ATN, acute tubular necrosis Collapsing focal segmental glomerulosclerosis EULAR/PRINTO/PRES, European League Against Rheumatism/Paediatric Rheumatology International Trials Organisation/Paediatric Rheumatology European Society HIV-associated nephropathy HIVAN, HIV-associated nephropathy HVICK, HIV immune complex kidney disease NACO, National AIDS Control Organization NGAL, neutrophil gelatinase associated lipocalin NHL, non-Hodgkin lymphoma PAH, pulmonary artery hypertension PAN, polyarteritis nodosa TIN, tubule-interstitial nephritis cART, combination anti-retroviral therapy eGFR, estimated glomerular filtration rate interstitial nephritis minimal change disease non-Hodgkin lymphoma proteinuria

Mesh : Asia Child Child, Preschool Female HIV Infections / complications Humans Infant Infant, Newborn Kidney Diseases / pathology Male Retrospective Studies

来  源:   DOI:10.1080/20469047.2018.1463126

Abstract:
There is a paucity of literature on renal diseases associated with HIV infection in Asian countries. Renal disease in HIV-infected children can involve the glomerulus, interstitium, tubules or blood vessels of the kidney. In this case series, five HIV-infected children with various forms of renal disease are reported. The renal pathology included HIV-associated nephropathy, collapsing focal segmental glomerulosclerosis without tubular changes, tubule-interstitial nephritis and minimal change disease (MCD). Case five fulfilled the classification criteria for childhood polyarteritis nodosa (PAN). It is important to screen all HIV-infected children for renal disease to enable detection at an early stage.
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