PDF(Sci-hub)
Abstract：
The worldwide interest in the use of medicinal plants has been growing, and its beneficial effects being rediscovered for the development of new drugs. Based on their vast ethnopharmacological applications, which inspired current research in drug discovery, natural products can provide new and important leads against various pharmacological targets. This work pioneers an extensive and an updated literature review on the current state of research on Rosmarinus officinalis L., elucidating which compounds and biological activities are the most relevant. Therefore, a search was made in the databases PubMed, ScienceDirect and Web of Science with the terms \'rosemary\', \'Rosmarinus officinalis\', \'rosmarinic acid\' \'carnosol\' and \'carnosic acid\', which included 286 articles published since 1990 about rosemary\'s pharmacological activities and their isolated compounds. According to these references, there has been an increasing interest in the therapeutic properties of this plant, regarding carnosic acid, carnosol, rosmarinic acid and the essential oil. The present manuscript provides an updated review upon the most reported activities on R. officinalis and its active constituents.
摘要：
全世界对药用植物的使用的兴趣一直在增长，它的有益作用被重新发现，以开发新药。基于它们广泛的民族药理学应用，这激发了目前药物发现的研究，天然产物可以针对各种药理靶标提供新的重要线索。这项工作率先对迷迭香的研究现状进行了广泛而最新的文献综述，阐明哪些化合物和生物活性是最相关的。因此,在PubMed数据库中进行了搜索，ScienceDirect和WebofScience，带有“迷迭香”的术语，\'迷迭香\',\'迷迭香酸\'\'鼠尾草\'和\'鼠尾草酸\'，其中包括自1990年以来发表的286篇关于迷迭香的药理活性及其分离化合物的文章。根据这些参考文献，人们对这种植物的治疗特性越来越感兴趣，关于鼠尾草酸，Carnosol,迷迭香酸和精油。本手稿提供了有关雷公藤及其活性成分报道最多的活动的最新评论。
