Abstract：
Relapse after discontinuation of ECT is significant in patients with schizophrenia. The purpose of this systematic review was to examine use of M-ECT in schizophrenia to guide clinical decision making for relapse prevention in schizophrenia. We reviewed studies examining the role of continuation (C-ECT) and maintenance electroconvulsive therapy (M-ECT) in schizophrenia. Following PRISMA guidelines, we included randomized controlled trials, open label trials, retrospective chart reviews, case reports, and case series in this review. We evaluated adjunctive pharmacological regimens; ECT treatment parameters, including frequency, duration of continued treatment, electrode placement; clinical outcomes including cognitive side effects and relapse rates from included studies. Our findings suggest M-ECT could provide an effective form of relapse prevention in these patients and persistent cognitive side effects are minimal.
摘要：
精神分裂症患者停止ECT后复发具有重要意义。本系统综述的目的是研究M-ECT在精神分裂症中的应用，以指导精神分裂症复发预防的临床决策。我们回顾了研究延续（C-ECT）和维持电惊厥治疗（M-ECT）在精神分裂症中的作用的研究。按照PRISMA准则,我们纳入了随机对照试验，开放标签试验，回顾性图表回顾，病例报告,和本评论中的案例系列。我们评估了辅助药物治疗方案；ECT治疗参数，包括频率,持续治疗的持续时间，电极放置；包括认知副作用和纳入研究的复发率在内的临床结果。我们的发现表明，M-ECT可以为这些患者提供预防复发的有效形式，并且持续的认知副作用很小。
