Abstract：
Host-pathogen interaction is one of the most important areas of study to understand the adhesion of the pathogen to the host organisms. To adhere on the host cell surface, bacteria assemble the diverse adhesive structures on its surface, which play a foremost role in targeting to the host cell. We have highlighted different bacterial adhesins which are either protein mediated or glycan mediated. The present article listed examples of different bacterial adhesin proteins involved in the interactions with their host, types and subtypes of the fimbriae and non-fimbriae bacterial adhesins. Different bacterial surface adhesin subunits interact with host via different host surface biomolecules. We have also discussed the interactome of some of the pathogens with their host. Therefore, the present study will help researchers to have a detailed understanding of different interacting bacterial adhesins and henceforth, develop new therapies, adhesin specific antibodies and vaccines, which can effectively control pathogenicity of the pathogens.
摘要：
宿主-病原体相互作用是了解病原体与宿主生物粘附的最重要的研究领域之一。粘附在宿主细胞表面，细菌在其表面组装不同的粘合剂结构，在靶向宿主细胞中起着最重要的作用。我们已经强调了蛋白质介导或聚糖介导的不同细菌粘附素。本文列出了参与与宿主相互作用的不同细菌粘附素蛋白的例子，菌毛和非菌毛细菌粘附素的类型和亚型。不同的细菌表面粘附素亚基通过不同的宿主表面生物分子与宿主相互作用。我们还讨论了一些病原体与其宿主的相互作用。因此,本研究将帮助研究人员详细了解不同的相互作用的细菌粘附素，开发新的疗法，粘附素特异性抗体和疫苗，能有效控制病原菌的致病性。
