关键词: Actinomyces Actinomycosis Intensive care unit Neurological symptoms Vascular infections Vasculitis

Mesh : Actinomyces / drug effects genetics isolation & purification Actinomycosis / diagnosis drug therapy immunology Anti-Bacterial Agents / therapeutic use Brain / diagnostic imaging Endothelium, Vascular / microbiology pathology Female Humans Intensive Care Units Lymph Nodes / microbiology Lymphadenopathy / diagnosis diagnostic imaging drug therapy microbiology Nervous System Diseases / complications microbiology RNA, Ribosomal, 16S Symbiosis Tomography, X-Ray Computed Treatment Outcome Vasculitis / microbiology Young Adult

来  源:   DOI:10.1016/j.jiph.2017.12.010

Abstract:
Actinomyces species are part of the commensal flora of the mucous membranes of the oropharynx, gastrointestinal tract and female genital tract. Actinomyces europaeus is a short, nonmotile, facultative anaerobic rod first described in 1997, susceptible in vitro to a wide range of b-lactam antibiotics which are regarded as first choice. In this report we described the case of A. europaeus infection in a young female patient admitted to Intensive Care Unit and the possible damage of vascular endothelium due to a chronic progressive actinomycosis that at first involved neck soft tissue, then cervical lymphnodes, and finally extended to the vascular structure.
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