关键词: Arf GTPase Grp1 PH domain Sec7 domain autoinhibition cytohesin electron microscopy guanine nucleotide exchange factor small-angle X-ray scattering
Mesh : ADP-Ribosylation Factor 6 ADP-Ribosylation Factors / chemistry genetics metabolism Allosteric Regulation Allosteric Site Amino Acid Sequence Animals Cloning, Molecular Escherichia coli / genetics metabolism Gene Expression Genetic Vectors / chemistry metabolism Guanine Nucleotide Exchange Factors / chemistry genetics metabolism Guanosine Triphosphate / chemistry metabolism Humans Kinetics Mice Molecular Dynamics Simulation Pleckstrin Homology Domains Protein Binding Protein Conformation, alpha-Helical Protein Conformation, beta-Strand Receptors, Cytoplasmic and Nuclear / chemistry genetics metabolism Recombinant Fusion Proteins / chemistry genetics metabolism Sequence Alignment Sequence Homology, Amino Acid Substrate Specificity
来 源:
DOI:10.1016/j.str.2017.11.019
PDF(Sci-hub)