黄芩叶提取物中熊果酸和齐墩果酸与 β - 内酰胺抗耐甲氧西林金黄色葡萄球菌的协同作用 : 体外和体内活性及其机制。
关键词: MRSA PBP2 Vitellaria paradoxa oleanolic acid skin infection triterpenic acid ursolic acid β-lactamases
Mesh : Animals Anti-Bacterial Agents / isolation & purification pharmacology therapeutic use Bacterial Proteins / metabolism Drug Resistance, Bacterial Drug Synergism Ericales / chemistry Female Hydrolysis Methicillin-Resistant Staphylococcus aureus / drug effects enzymology Mice, Inbred C57BL Microbial Sensitivity Tests Oleanolic Acid Plant Extracts / isolation & purification pharmacology therapeutic use Plant Leaves / chemistry Staphylococcal Infections / drug therapy microbiology Triterpenes beta-Lactamases / metabolism beta-Lactams / pharmacology Ursolic Acid
来 源:
DOI:10.3390/molecules22122245
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