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Abstract：
Ilex guayusa tea preparations are now commercially available as Runa tea. Little is known regarding the antioxidant and anti-inflammatory bioactivities of this tea. The I. guayusa teas had a total polyphenolic content between 54.39 and 67.23 mg GAE per g dry mass and peroxyl radical scavenging capacities between 1773.41 and 2019 μmol TE per g dry mass, nearly half of that for the Camellia sinensis teas. The I. guayusa teas afforded 60-80% protection from oxidative stress in the Caco-2 cellular antioxidant assay, comparable to the C. sinensis teas. The anti-inflammatory activity in lipopolysaccharide-stimulated RAW 264.7 cells of I. guayusa teas was similarly comparable to the C. sinensis teas with nitric oxide production reduced by 10-30%. Major compounds identified by mass spectrometry were the phenolic mono- and dicaffeoylquinic acid derivatives. I. guayusa teas are a good source of dietary phenolic compounds with cellular antioxidant and anti-inflammatory properties.
摘要：
Ilexguayusa茶制剂现在可以作为Runa茶购买。关于这种茶的抗氧化和抗炎生物活性知之甚少。I.guayusa茶的总多酚含量为54.39至67.23mgGAE/g干重，过氧自由基清除能力为1773.41至2019μmolTE/g干重，其中近一半用于山茶花茶。I.guayusa茶在Caco-2细胞抗氧化剂测定中提供了60-80％的氧化应激保护，相当于C.sinensis茶。I.guayusa茶的脂多糖刺激的RAW264.7细胞中的抗炎活性类似地与C.sinensis茶相当，一氧化氮的产生减少了10-30％。通过质谱鉴定的主要化合物是酚类单和二咖啡酰基奎尼酸衍生物。I.guayusa茶是具有细胞抗氧化和抗炎特性的膳食酚类化合物的良好来源。
