应激颗粒转录组揭示了应激颗粒中 mRNA 积累的原理。
关键词: RNA localization RNA-seq RNP granules amyotrophic lateral sclerosis eCLIP mRNP assemblies neurodegenerative diseases single molecule FISH stress granules
Mesh : Cell Line, Tumor Cytoplasmic Granules / genetics metabolism Humans RNA, Fungal / genetics metabolism RNA, Messenger / genetics metabolism Saccharomyces cerevisiae / genetics metabolism Transcriptome / physiology
来 源:
DOI:10.1016/j.molcel.2017.10.015
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