[Chimerism analysis after hematopoietic cell transplantation: Guidelines from the Francophone Society of bone marrow transplantation and cellular therapy (SFGM-TC)].

[造血细胞移植后的嵌合性分析 ： 来自法语国家骨髓移植和细胞治疗协会 （ SFGM - TC ） 的指南] 。

• 影响指数: 1.318
• 发表时间: Dec 2017
• 来源期刊: Bull Cancer
• DOI: 10.1016/j.bulcan.2017.08.010
• PMID: 29128084
• 文章类型: Journal Article
• 中科院分区: Q4
• 方向: 医学
• 作者列表: Dubois V,Alizadeh M,Bourhis JH,Etancelin P,Farchi O,Ferrand C,Goursaud L,Mollet I,Renac V,Varlet P,Yakoub-Agha I,Bay JO

关键词: Blood; Chimerism; Chimérisme; Maladie résiduelle; Minimal residual disease; PCR quantitative; Real time PCR; Sang

Mesh: Allografts; Chimerism; France; HLA Antigens / immunology; Hematologic Neoplasms / pathology therapy; Hematopoietic Stem Cell Transplantation; Humans; Microsatellite Repeats; Neoplasm, Residual; Societies, Medical

Abstract

Chimerism analysis is an important step for the patient follow-up after hematopoietic stem cell transplantation. It is used to quantify the donor and the recipient part of a cell population issued from blood or bone marrow sample. In addition to hemogram, this technique is necessary to appreciate the quality of engraftment. The aim of this article is to propose some recommendation about methods, result analysis and therapeutic decision in hematopoietic stem cell transplantation for malignant or non-malignant diseases.

摘要

嵌合分析是造血干细胞移植后患者随访的重要步骤。它用于量化从血液或骨髓样品中发出的细胞群的供体和受体部分。除了血象,这种技术是必要的，以欣赏雕刻的质量。本文的目的是提出一些关于方法的建议，造血干细胞移植治疗恶性或非恶性疾病的结果分析和治疗决策。