An acute gastroenteritis outbreak caused by GII.P16-GII.2 norovirus associated with airborne transmission via the air conditioning unit in a kindergarten in Lianyungang, China.

• 影响指数: 12.074
• 发表时间: Dec 2017
• 来源期刊: Int J Infect Dis
• DOI: 10.1016/j.ijid.2017.10.003
• PMID: 29031606
• 文章类型: Case Reports
• 中科院分区: Q2
• 方向: 医学
• 作者列表: Zhang TL,Lu J,Ying L,Zhu XL,Zhao LH,Zhou MY,Wang JL,Chen GC,Xu L

关键词: Disease outbreak; Epidemiological investigation; GII.P16-GII.2; Kindergarten

Mesh: Acute Disease; Air Conditioning; Air Pollution, Indoor; Caliciviridae Infections / diagnosis epidemiology transmission; Child, Preschool; China / epidemiology; Disease Outbreaks; Feces / virology; Female; Gastroenteritis / diagnosis epidemiology virology; Humans; Incidence; Male; Norovirus / isolation & purification; Schools; Specimen Handling

Abstract

Noroviruses are a common cause of acute gastroenteritis outbreaks in institutions including schools and kindergartens around the world. An outbreak caused by GII.P16-GII.2 norovirus in a kindergarten in Lianyungang, Jiangsu Province, China is reported here. An epidemiological investigation was conducted, and pathogen detection was performed. The descriptive analysis indicated that this outbreak in middle class 1 had a point source. Twenty cases of acute gastroenteritis occurred in this class within a period of 8.5h; the attack rate was 52.6% (20/38). Airborne transmission via the air conditioning unit in a confined restroom could have played a critical role in this outbreak. Sequence analysis of GII-positive samples confirmed that the norovirus GII.P16-GII.2 variant was the etiological agent of this outbreak.