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Abstract：
Studies on brown algal cell walls have entered a new phase with the concomitant discovery of novel polysaccharides present in cell walls and the establishment of a comprehensive generic model for cell wall architecture. Brown algal cell walls are composites of structurally complex polysaccharides. In this review we discuss the most recent progress in the structural composition of brown algal cell walls, emphasizing the significance of extraction and screening techniques, and the biological activities of the corresponding polysaccharides, with a specific focus on the fucose-containing sulfated polysaccharides. They include valuable marine molecules that exert a broad range of pharmacological properties such as antioxidant and anti-inflammatory activities, functions in the regulation of immune responses and of haemostasis, anti-infectious and anticancer actions. We identify the key remaining challenges in this research field.
摘要：
随着细胞壁中存在的新型多糖的发现以及细胞壁结构的综合通用模型的建立，对褐藻细胞壁的研究进入了一个新阶段。褐藻细胞壁是结构复杂的多糖的复合物。在这篇综述中，我们讨论了棕色藻类细胞壁结构组成的最新进展，强调提取和筛选技术的重要性，以及相应多糖的生物活性，特别关注含岩藻糖的硫酸化多糖。它们包括有价值的海洋分子，发挥广泛的药理特性，如抗氧化和抗炎活性，在调节免疫反应和止血方面的功能，抗感染和抗癌作用。我们确定了该研究领域的关键挑战。
