关键词: Candida auris Chlorhexidine gluconate Chlorine Povidone-iodine Quantitative suspension test

Mesh : Anti-Infective Agents, Local / pharmacology Candida / drug effects physiology Candida albicans / drug effects physiology Disinfectants / pharmacology Humans Microbial Sensitivity Tests Microbial Viability / drug effects

来  源:   DOI:10.1016/j.jhin.2017.08.019   PDF(Sci-hub)

Abstract:
Candida auris appears to be transmitted readily between patients, yet information regarding the efficacy of environmental disinfection and skin decolonization is lacking. A quantitative suspension test (EN 13624:2013) was used to evaluate the yeasticidal activity of different chemical disinfectants and antiseptics against C. auris and Candida albicans. When tested in suspension, both a chlorine-based disinfectant and iodine-based skin antiseptic were effective against C. auris, suggesting that their use could reduce environmental contamination and skin colonization, respectively, if applied appropriately. Chlorhexidine-based products may also be effective. However, in this study, activity depended on formulation, specifically the presence of isopropyl alcohol.
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