关键词: HLA ligands KIR PCR-SSP typing

Mesh : Gene Frequency Genotype HLA-A11 Antigen / genetics HLA-B Antigens / genetics HLA-C Antigens / genetics Haplotypes Humans Linkage Disequilibrium Polymerase Chain Reaction Polymorphism, Genetic Receptors, KIR / genetics Thailand

来  源:   DOI:10.1016/j.humimm.2017.04.002   PDF(Sci-hub)

Abstract:
The diversity of 17 KIR and HLA ligands (HLA-C1, C2, Bw4, A11) were investigated in two hundred and thirty-five unrelated healthy donors in Northeastern Thais (NETs) by the polymerase chain reaction with sequence-specific primer (PCR-SSP) method. The Hardy-Weinberg Equilibrium (HWE) was used to verify genotyping method for dimorphic KIR and HLA. They were in HWE (p>0.05). KIR and HLA ligands frequencies, genotypes, haplotypes and linkage disequilibrium (LD) were presented. The genetic data are available in allele Frequencies Net Database.
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