关键词: Anti-tumor drugs Benzamides HDACIs HDACs In vivo oral activity
Mesh : Animals Antineoplastic Agents / chemistry pharmacology therapeutic use Benzamides / chemistry pharmacology therapeutic use Cell Proliferation / drug effects Colon / drug effects metabolism Colorectal Neoplasms / drug therapy metabolism HCT116 Cells Histone Deacetylase 1 / antagonists & inhibitors metabolism Histone Deacetylase Inhibitors / chemistry pharmacology therapeutic use Histone Deacetylases / metabolism Humans Leukemia / drug therapy metabolism Male Mice, Nude Rectum / drug effects metabolism Structure-Activity Relationship U937 Cells
来 源:
DOI:10.1016/j.ejmech.2017.03.069
PDF(Sci-hub)