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Abstract：
CONCLUSIONS: There is a high propensity for locoregional and isolated regional failure in stage II patients, even though treated with combined therapy. In stage I patients the risk of isolated regional failure was moderate, at levels below 10%.
BACKGROUND: The neck treatment of early stages of oral tongue squamous cell carcinoma (OTSCC) are still debatable, considering that previous studies have produced diverting results. The purpose of this study is to report on the outcome of patients with stages I-II, with special respect to regional outcome.
METHODS: All patients treated for OTSCC at Karolinska University Hospital between 2008-2014 were included. Patient demographics, intention of treatment, treatment modality, time of follow-up and status at follow-up, recurrence, and place of recurrence were recorded.
RESULTS: Of 230 patients, 149 presented within stages I and II. Of those, 105 were electively treated to the neck. In stage I, the risk of presence of disease in the neck specimen was four out of 63 (6%), whereas 17 out of 41 (41%) were positive in stage II patients. The overall risk of isolated regional failure at any time in stage I patients was six out of 89 and in stage II 25 out of 60.
BACKGROUND: The neck treatment of early stages of oral tongue squamous cell carcinoma (OTSCC) are still debatable, considering that previous studies have produced diverting results. The purpose of this study is to report on the outcome of patients with stages I-II, with special respect to regional outcome.
METHODS: All patients treated for OTSCC at Karolinska University Hospital between 2008-2014 were included. Patient demographics, intention of treatment, treatment modality, time of follow-up and status at follow-up, recurrence, and place of recurrence were recorded.
RESULTS: Of 230 patients, 149 presented within stages I and II. Of those, 105 were electively treated to the neck. In stage I, the risk of presence of disease in the neck specimen was four out of 63 (6%), whereas 17 out of 41 (41%) were positive in stage II patients. The overall risk of isolated regional failure at any time in stage I patients was six out of 89 and in stage II 25 out of 60.
摘要：
结论：在II期患者中存在局部和孤立的局部失败倾向，即使用联合疗法治疗。在I期患者中，孤立的区域失败的风险中等，低于10%的水平。
背景：早期口腔舌鳞状细胞癌（OTSCC）的颈部治疗仍有争议，考虑到以前的研究已经产生了不同的结果。这项研究的目的是报告I-II期患者的预后，特别是区域成果。
方法：纳入2008-2014年在卡罗林斯卡大学医院接受OTSCC治疗的所有患者。患者人口统计学，治疗意向,治疗方式，随访时间和随访状态，复发,记录复发地点。
结果：在230名患者中，149在第一阶段和第二阶段提出。其中,对105例颈部进行选择性治疗。在第一阶段,颈部标本中存在疾病的风险为63人中的4人(6%)，而II期患者41人中有17人(41%)为阳性.在I期患者中，任何时候孤立的区域失败的总体风险是89人中的6人，在II期中，60人中的25人。
背景：早期口腔舌鳞状细胞癌（OTSCC）的颈部治疗仍有争议，考虑到以前的研究已经产生了不同的结果。这项研究的目的是报告I-II期患者的预后，特别是区域成果。
方法：纳入2008-2014年在卡罗林斯卡大学医院接受OTSCC治疗的所有患者。患者人口统计学，治疗意向,治疗方式，随访时间和随访状态，复发,记录复发地点。
结果：在230名患者中，149在第一阶段和第二阶段提出。其中,对105例颈部进行选择性治疗。在第一阶段,颈部标本中存在疾病的风险为63人中的4人(6%)，而II期患者41人中有17人(41%)为阳性.在I期患者中，任何时候孤立的区域失败的总体风险是89人中的6人，在II期中，60人中的25人。
