%0 Journal Article
%T Regional recurrence in early stage I-II oral tongue cancer: a single institutional study and review of the literature.
%A Kamali A
%A Gahm C
%A Palmgren B
%A Marklund L
%A Halle M
%A Hammarstedt-Nordenvall L
%J Acta Otolaryngol
%V 137
%N 7
%D Jul 2017
%M 28361597
%F 1.698
%R 10.1080/00016489.2017.1279751
%X <B>CONCLUSIONS: </B>There is a high propensity for locoregional and isolated regional failure in stage II patients, even though treated with combined therapy. In stage I patients the risk of isolated regional failure was moderate, at levels below 10%.<BR><B>BACKGROUND: </B>The neck treatment of early stages of oral tongue squamous cell carcinoma (OTSCC) are still debatable, considering that previous studies have produced diverting results. The purpose of this study is to report on the outcome of patients with stages I-II, with special respect to regional outcome.<BR><B>METHODS: </B>All patients treated for OTSCC at Karolinska University Hospital between 2008-2014 were included. Patient demographics, intention of treatment, treatment modality, time of follow-up and status at follow-up, recurrence, and place of recurrence were recorded.<BR><B>RESULTS: </B>Of 230 patients, 149 presented within stages I and II. Of those, 105 were electively treated to the neck. In stage I, the risk of presence of disease in the neck specimen was four out of 63 (6%), whereas 17 out of 41 (41%) were positive in stage II patients. The overall risk of isolated regional failure at any time in stage I patients was six out of 89 and in stage II 25 out of 60.