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Abstract：
BACKGROUND: Pseudomonas oryzihabitans is a Pseudomonas bacterial organism rarely implicated in human infections. The bacterium has been isolated in a few reported cases of neurosurgical infections and patients with end-stage cirrhosis, sickle cell disease, and community-acquired urinary tract infections. Limited information exists in developing countries, however, because of the lack of advanced microbiological tools for identification and characterization of this bacterium. This case report describes the isolation of a rare Pseudomonas bacterium in a patient presenting with sepsis and skin infection.
METHODS: A 1-year-old girl was presented to a hospital in the northeastern part of Ghana with a 1-week history of pustular rashes on her scalp and neck, which occasionally ruptured, along with discharge of yellowish purulent fluid. The child is of Mole-Dagbon ethnicity and hails from the northern part of Ghana. Pseudomonas oryzihabitans was identified in the patient\'s blood culture using the 16S ribosomal deoxyribonucleic acid sequencing technique. The rash on the patient\'s scalp and skin resolved after continuous treatment with gentamicin while her condition improved clinically.
CONCLUSIONS: This finding suggests the potential of this bacterium to cause disease in unsuspected situations and emphasizes the need to have evidence for the use of the appropriate antibiotic in clinical settings, particularly in rural settings in Africa. It also brings to the fore the unreliability of conventional methods for identification of Pseudomonas bacteria in clinical samples and thus supports the use of 16S ribosomal deoxyribonucleic acid in making the diagnosis.
METHODS: A 1-year-old girl was presented to a hospital in the northeastern part of Ghana with a 1-week history of pustular rashes on her scalp and neck, which occasionally ruptured, along with discharge of yellowish purulent fluid. The child is of Mole-Dagbon ethnicity and hails from the northern part of Ghana. Pseudomonas oryzihabitans was identified in the patient\'s blood culture using the 16S ribosomal deoxyribonucleic acid sequencing technique. The rash on the patient\'s scalp and skin resolved after continuous treatment with gentamicin while her condition improved clinically.
CONCLUSIONS: This finding suggests the potential of this bacterium to cause disease in unsuspected situations and emphasizes the need to have evidence for the use of the appropriate antibiotic in clinical settings, particularly in rural settings in Africa. It also brings to the fore the unreliability of conventional methods for identification of Pseudomonas bacteria in clinical samples and thus supports the use of 16S ribosomal deoxyribonucleic acid in making the diagnosis.
摘要：
背景：产卵假单胞菌是一种很少与人类感染有关的假单胞菌细菌。在少数报道的神经外科感染和终末期肝硬化患者中已分离出细菌，镰状细胞病,和社区获得性尿路感染。发展中国家的信息有限，然而,因为缺乏先进的微生物工具来鉴定和表征这种细菌。此病例报告描述了在败血症和皮肤感染的患者中分离出一种罕见的假单胞菌。
方法：一名1岁女孩被送往加纳东北部的一家医院，她的头皮和颈部有1周脓疱性皮疹，偶尔破裂，伴随着淡黄色脓液的排出。这个孩子是Mole-Dagbon族，来自加纳北部。使用16S核糖体脱氧核糖核酸测序技术，在患者的血液培养中鉴定出乳杆菌假单胞菌。连续使用庆大霉素治疗后，患者头皮和皮肤上的皮疹消退，而病情在临床上有所改善。
结论：这一发现表明了这种细菌在意外情况下可能引起疾病，并强调需要有证据证明在临床环境中使用适当的抗生素，特别是在非洲的农村地区。它还突出了用于鉴定临床样品中的假单胞菌属细菌的常规方法的不可靠性,因此支持使用16S核糖体脱氧核糖核酸进行诊断。
方法：一名1岁女孩被送往加纳东北部的一家医院，她的头皮和颈部有1周脓疱性皮疹，偶尔破裂，伴随着淡黄色脓液的排出。这个孩子是Mole-Dagbon族，来自加纳北部。使用16S核糖体脱氧核糖核酸测序技术，在患者的血液培养中鉴定出乳杆菌假单胞菌。连续使用庆大霉素治疗后，患者头皮和皮肤上的皮疹消退，而病情在临床上有所改善。
结论：这一发现表明了这种细菌在意外情况下可能引起疾病，并强调需要有证据证明在临床环境中使用适当的抗生素，特别是在非洲的农村地区。它还突出了用于鉴定临床样品中的假单胞菌属细菌的常规方法的不可靠性,因此支持使用16S核糖体脱氧核糖核酸进行诊断。
