关键词: 2,4-diaminoquinazoline Anti-cancer PAK4 inhibitor Synthesis p21-activated kinase
Mesh : A549 Cells Cell Cycle / drug effects Cell Movement / drug effects Dose-Response Relationship, Drug Humans Molecular Docking Simulation Molecular Structure Protein Kinase Inhibitors / chemical synthesis chemistry pharmacology Quinazolines / chemical synthesis chemistry pharmacology Structure-Activity Relationship p21-Activated Kinases / antagonists & inhibitors metabolism
来 源: DOI:10.1016/j.ejmech.2017.02.063