关键词: Legionella Legionnaire's disease Legionnaire's disease epidemiology Legionnaire's diseases diagnosis Legionnaire's diseases microbiology

Mesh : Adult Anti-Bacterial Agents Disease Outbreaks / statistics & numerical data Female Humans Legionella pneumophila Legionnaires' Disease / diagnosis epidemiology microbiology mortality Male Middle Aged Risk Factors Water Microbiology

来  源:   DOI:10.1016/j.idc.2016.10.002   PDF(Sci-hub)

Abstract:
Legionnaire\'s disease (LD) is the pneumonic form of legionellosis caused by aerobic gram-negative bacilli of the genus Legionella. Individuals become infected when they inhale aerosolized water droplets contaminated with Legionella species. Forty years after the identification of Legionella pneumophila as the cause of the 1976 pneumonia outbreak in a hotel in Philadelphia, we have non-culture-based diagnostic tests, effective antibiotics, and preventive measures to handle LD. With a mortality rate still around 10%, underreporting, and sporadic outbreaks, there is still much work to be done. In this article, the authors review the microbiology, laboratory diagnosis, and epidemiology of LD.
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