关键词: Diffusion tensor imaging Endoscopic third ventriculostomy Neurocognitive Shunt Ventricle Ventricular size Volume

Mesh : Cerebrospinal Fluid Shunts / adverse effects methods Cognition / physiology Cognitive Dysfunction / etiology Humans Hydrocephalus / complications surgery Third Ventricle / surgery Treatment Outcome Ventriculostomy / adverse effects methods

来  源:   DOI:10.1007/s00381-016-3032-3   PDF(Sci-hub)

Abstract:
BACKGROUND: Shunts are generally associated with a smaller post-treatment ventricular size in comparison to endoscopic third ventriculostomy (ETV).
METHODS: To determine whether such a difference in ventricular size has neurocognitive implications, we reviewed the current literature pertaining to the (1) neurocognitive sequelae of hydrocephalus, (2) neurocognitive outcome after ETV, (3) extent of reversal of neurocognitive changes associated with hydrocephalus after shunting, and (4) data on correlation between post-treatment ventricular volume and neurocognitive outcome after ETV.
RESULTS: Collectively, the results of the available studies should call into question the correlation between the residual postoperative ventricular volume and neurocognitive outcome.
CONCLUSIONS: The available literature is so far in support of ETV as a valid and effective treatment modality in hydrocephalic patients. No sufficient evidence is available to justify resorting to shunting on the premise that it is associated with a better neurocognitive outcome.
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