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Abstract：
Axial spondyloarthritis (SpA) is a spectrum of inflammatory disease with stages characterized by both nonradiographic and radiographic sacroiliitis. Nonradiographic axial SpA is associated with health-related quality-of-life impairment and may progress to ankylosing spondylitis. Axial SpA has a low prevalence in some countries in North Africa and the Middle East, and pooling of data and resources is needed to increase understanding of the regional picture. Early diagnosis and effective treatment are required to reduce disease burden and prevent progression. Anti-TNF therapy is recommended for patients with persistently high disease activity despite conventional treatment, and has been shown to be effective in patients without radiographic damage. Diagnostic delays can be an obstacle to early treatment and appropriate referral strategies are needed. In some countries, restricted access to magnetic resonance imaging and anti-TNF agents presents a challenge. In this article, a group of experts from North Africa and the Middle East evaluated the diagnosis and management of axial SpA with particular reference to this region.
摘要：
轴性脊柱关节炎（SpA）是一系列炎症性疾病，其特征在于非放射学和放射学骶髂关节炎。非放射学轴向SpA与健康相关的生活质量损害有关，并可能发展为强直性脊柱炎。轴向SpA在北非和中东的一些国家患病率较低，需要汇集数据和资源，以增加对区域情况的了解。需要早期诊断和有效治疗以减轻疾病负担并防止进展。尽管常规治疗，但仍建议对疾病活动性持续较高的患者进行抗TNF治疗。并已被证明对无影像学损害的患者有效。诊断延迟可能是早期治疗的障碍，需要适当的转诊策略。在一些国家,限制磁共振成像和抗TNF药物的使用是一个挑战.在这篇文章中,来自北非和中东的专家组特别针对该地区评估了轴向SpA的诊断和治疗.
