关键词: comparative effectiveness glaucoma medication glaucoma surgery intraocular pressure open-angle glaucoma registry

Mesh : Adrenergic alpha-2 Receptor Agonists / therapeutic use Adrenergic beta-Antagonists / therapeutic use Adult Aged Aged, 80 and over Blacks / statistics & numerical data Carbonic Anhydrase Inhibitors / therapeutic use Female Glaucoma, Open-Angle / physiopathology therapy Hispanic or Latino / statistics & numerical data Humans Intraocular Pressure / drug effects physiology Laser Therapy / methods Male Middle Aged Parasympathomimetics / therapeutic use Prostaglandins, Synthetic / therapeutic use Trabeculectomy Treatment Outcome Young Adult

来  源:   DOI:10.2217/cer.15.58   PDF(Sci-hub)

Abstract:
OBJECTIVE: The RiGOR study\'s primary outcome measure was a 15% reduction in intraocular pressure (IOP) for patients with open-angle glaucoma at 1 year.
METHODS: Patients received treatment according to the ophthalmologist\'s usual practice.
RESULTS: A higher proportion of patients in the incisional and other surgery group achieved a 15% reduction in IOP than in the laser surgery or additional medication groups (82, 57, and 57% respectively). In multivariate regression analyses, incisional surgery patients were 2.7-times as likely as patients treated with additional medication to achieve a 15% reduction in IOP (odds ratio: 2.67; 95% CI: 2.01-3.57).
CONCLUSIONS: Incisional and other surgical procedures are effective treatments. There were no differences in treatment response by race or ethnicity.
摘要:
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