Abstract：
Lifestyle-related diseases other than type 2 diabetes mellitus and chronic kidney disease have also been reported in recent studies to have a possible effect on bone metabolism. In particular, evidence is accumulating regarding decreases in bone mineral density and an increased risk of fracture due to chronic obstructive pulmonary disease (COPD). In COPD, the fracture risk increases in both men and women, and the condition is considered a risk factor independent of glucocorticoid administration. Moreover, since kyphosis resulting from vertebral fractures adversely affects respiratory function, assessment of osteoporosis is recommended for all patients with COPD, regardless of sex. As for dyslipidemia and hypertension, due to the possible involvement of various factors, no consensus has been reached regarding the effects of the condition itself on bone.
摘要：
除2型糖尿病和慢性肾脏疾病以外的生活方式相关疾病在最近的研究中也被报道对骨代谢具有可能的影响。特别是,越来越多的证据表明,慢性阻塞性肺疾病(COPD)导致骨矿物质密度降低和骨折风险增加.在COPD中，男性和女性的骨折风险都会增加，这种情况被认为是独立于糖皮质激素给药的危险因素。此外，由于椎体骨折导致的后凸畸形会对呼吸功能产生不利影响，建议对所有COPD患者进行骨质疏松评估,不管性别。至于血脂异常和高血压，由于各种因素的可能参与，关于病情本身对骨骼的影响尚未达成共识。
