Abstract：
Parapharyngeal space (PPS) tumors are rare and account for about 0.5% of all head and neck neoplasms. Most PPS tumors are benign (up to 80%) while the remaining 20% are malignant. These tumors are either primaries; most commonly arising from salivary glands or metastatic tumors or due to direct extension of tumors from the adjacent sites. Distant metastasis from breast cancers more commonly involves the lungs, bones, brain and liver. Metastasis to the PPS from a primary breast carcinoma is rare, with only one case reported in literature. We, to the best of our knowledge report the second case of a carcinoma breast metastasizing to the PPS and further discuss the diagnostic and therapeutic challenges involved in its management. A fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography scan apart from explicitly defining the extent of the PPS tumor, majorly influenced the therapeutic decision making process by ruling out other sites of metastasis.
摘要：
咽旁间隙（PPS）肿瘤很少见，约占所有头颈部肿瘤的0.5％。大多数PPS肿瘤是良性的（高达80％），而其余20％是恶性的。这些肿瘤要么是原发性肿瘤；最常见的是由唾液腺或转移性肿瘤引起的，或者是由于肿瘤从相邻部位直接延伸而引起的。乳腺癌的远处转移通常涉及肺部，骨头,大脑和肝脏。从原发性乳腺癌转移到PPS是罕见的，文献中只报道了一例。我们,据我们所知，报告了第二例乳腺癌转移为PPS的病例，并进一步讨论了其治疗中涉及的诊断和治疗挑战。氟-18氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描除了明确定义PPS肿瘤的范围外，主要通过排除其他转移部位来影响治疗决策过程。
