关键词: Basal cell carcinoma Beta-catenin Bêta-caténine Carcinome basocellulaire à différenciation matricielle Cellules fantômes Matrical differentiation Shadow cells

Mesh : Aged Carcinoma, Basal Cell / pathology Female Hand Humans Skin Neoplasms / pathology

来  源:   DOI:10.1016/j.annpat.2015.01.001   PDF(Sci-hub)

Abstract:
Basal cell carcinoma with matrical differentiation is a very rare variant of basal cell carcinoma. To our knowledge, less than 30 cases have been reported. This tumor is composed of basaloid lobules showing a differentiation toward the pilar matrix cells. Recently, it has been demonstrated that beta-catenin would interfer with physiopathogenesis of matrical tumors, in particular pilomatricomas, but also basal cell carcinomas with matrical differentiation. This is a new case, with immunohistochemical and molecular analysis of beta-catenin, in order to explain its histogenesis.
摘要:
暂无翻译
公众号