{Reference Type}: Case Reports
{Title}: [Basal cell carcinoma with matrical differentiation].
{Author}: Goldman-Lévy G;Frouin E;Soubeyran I;Maury G;Guillot B;Costes V;
{Journal}: Ann Pathol
{Volume}: 35
{Issue}: 2
{Year}: Apr 2015
{Factor}: 0.411
{DOI}: 10.1016/j.annpat.2015.01.001
{Abstract}: Basal cell carcinoma with matrical differentiation is a very rare variant of basal cell carcinoma. To our knowledge, less than 30 cases have been reported. This tumor is composed of basaloid lobules showing a differentiation toward the pilar matrix cells. Recently, it has been demonstrated that beta-catenin would interfer with physiopathogenesis of matrical tumors, in particular pilomatricomas, but also basal cell carcinomas with matrical differentiation. This is a new case, with immunohistochemical and molecular analysis of beta-catenin, in order to explain its histogenesis.