Mesh : Administration, Oral Anemia, Iron-Deficiency / etiology therapy Animals Anticestodal Agents / administration & dosage Diarrhea Eating Feces / parasitology Humans Hymenolepiasis / diagnosis drug therapy parasitology transmission Hymenolepis diminuta / classification isolation & purification Infant Insect Vectors / parasitology Male Niclosamide / administration & dosage Rare Diseases / diagnosis parasitology Vomiting

来  源:   DOI:10.5578/mb.8695

Abstract:
Unlike Hymenolepis nana that transmits directly from person to person, the transmission of Hymenolepis diminuta to human is via accidentally ingesting of arthropods carrying cysticercoid larvae as intermediate host. In places with poor hygienic conditions, this cestod may cause seldom infections especially in children. Studies carried out on various populations have reported the prevalence rate of H.diminuta between 0.001% and 5.5%. Although the reported cases are mostly children, the disease can be seen in every age group. In this report, a pediatric case of H.diminuta infection is presented. A twenty one-month-old male patient with the symptoms of vomiting 3-4 times a day along with mud-like diarrhea continuing for a week was admitted to the pediatric outpatient clinic. According to the history, it was learned that the house where he lived was above a barn and there was a history of insect swallowing. Laboratory findings revealed iron-deficiency anemia. The macroscopic appearance of the stool was in a pale clay-like form, and by direct microscopic examination with lugol solution, 70-75 μm in diameter, thick-shelled and six central hookleted eggs that are characteristic for H.diminuta were identified. A six-day course of oral niclosamide was administered to the patient beginning with 500 mg on the first day and 250 mg on the following five days, together with the treatment for the iron deficiency anemia. After fifteen days, the oral niclosamide treatment was repeated. No H.diminuta eggs were detected in the parasitological examination performed one month after completion of the second round of treatment. This case has been presented to call attention to the importance of patient anamnesis and microscopic examination in the diagnosis of H.diminuta infection which is a rarely seen parasitosis.
摘要:
与直接在人与人之间传播的处女膜不同,通过意外摄入携带囊虫幼虫作为中间宿主的节肢动物,将膜虫减少传播给人类。在卫生条件差的地方,这种cestod很少引起感染,尤其是在儿童中。在各种人群中进行的研究报告了H.diminuta的患病率在0.001%至5.5%之间。尽管报告的病例大多是儿童,这种疾病在每个年龄组都可以看到。在这份报告中,介绍了一例小儿H.diminuta感染病例。一名21个月大的男性患者,每天呕吐3-4次,并伴有持续一周的泥状腹泻,被送往儿科门诊。根据历史,据悉,他住的房子在谷仓上方,有昆虫吞咽的历史。实验室发现缺铁性贫血。大便的宏观外观呈苍白的粘土状,用Lugol溶液直接显微镜检查,直径70-75μm,鉴定出了H.diminuta特有的厚壳和六个中央钩状卵。对患者进行为期六天的口服氯硝柳胺疗程,第一天开始为500毫克,接下来的五天为250毫克,一起治疗缺铁性贫血。十五天后,重复口服氯硝柳胺治疗。在第二轮治疗完成后一个月进行的寄生虫学检查中未检测到小红藻卵。该病例已被提出,以引起人们对患者病史和显微镜检查在诊断H.diminuta感染中的重要性的关注,H.diminuta感染是一种罕见的寄生虫病。
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