CXCR4 活性突变体的转基因表达研究。造血干 / 祖细胞归巢和移植效率上调的潜在前景。
关键词: Ala, Alanine Asn, Asparagine BM, Bone Marrow BMEC, Bone marrow endothelial cells BSA, Bovine Serum Albumin CAMs, Constitutive Active Mutants CXCR4 Conc., Concentration ECM, Extracellular matrix FBS, Fetal Bovine Serum FN, Fibronectin HSPCs HSPCs, Hematopoietic Stem/ Progenitor Cells HUVECs, Human Umbilical Vein Endothelial cells IMDM, Iscove's Modified Dulbecco Media LIF, Leukemia Inhibitory Factor MCS, Multi Cloning Site Ser, Serine TM3, Transmembrane three domain engraftment homing
Mesh : Cell Adhesion Cell Movement Chemokine CXCL12 / genetics Hematopoietic Stem Cell Transplantation Hematopoietic Stem Cells / cytology Humans K562 Cells Receptors, CXCR4 / genetics Signal Transduction Transgenes
来 源:
DOI:10.4161/cam.29285
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