METHODS: A sample of lung cancer patients scheduled for curative intent chemotherapy was randomly assigned to the exercise intervention (EX) condition or usual care (UC) condition. The EX condition participated in a three times weekly exercise program using resistance bands for the duration of chemotherapy.
RESULTS: A total of 14 lung cancer patients completed the trial. EX condition participants completed 79% of planned exercise sessions. The EX condition was able to maintain WBCs over the course of the intervention compared to declines in the UC condition (p = .008; d = 1.68). There were no significant differences in change scores in RBCs.
CONCLUSIONS: Exercise with resistance bands may help attenuate declines in WBCs in lung cancer patients receiving curative intent chemotherapy. Larger trials are warranted to validate these findings. Ultimately these findings could be informative for the development of supportive care strategies for lung cancer patients receiving chemotherapy.
BACKGROUND: Clinical Trials Registration #: NCT01130714.
方法:将计划进行根治性意向化疗的肺癌患者样本随机分配到运动干预(EX)条件或常规治疗(UC)条件。EX患者在化疗期间使用阻力带参加每周三次的锻炼计划。
结果:共有14名肺癌患者完成了试验。参与者完成了79%的计划锻炼。与UC条件的下降相比,EX条件能够在干预过程中维持WBC(p=.008;d=1.68)。红细胞的变化评分没有显着差异。
结论:抗阻带运动可能有助于减轻接受根治性化疗的肺癌患者白细胞下降。需要更大的试验来验证这些发现。最终,这些发现可以为接受化疗的肺癌患者的支持性护理策略的开发提供信息。
背景:临床试验登记号:NCT01130714。