Raf 激酶募集对 GTP 酶 H - ras 的功效取决于 H - ras 膜构象异构体特异性纳米簇。
关键词: Cancer Fluorescence Correlation Spectroscopy Fluorescence Recovery after Photobleaching (FRAP) Fluorescence Resonance Energy Transfer (FRET) Fluorescence-lifetime Microscopy Imaging (FLIM) Membrane Nanocluster Ras Signaling Stimulated Emission Depletion (STED)
Mesh : Animals Cell Line Cell Membrane / enzymology genetics Cricetinae Galectin 1 / genetics metabolism Mice Mice, Knockout Models, Biological Neoplasms / enzymology metabolism pathology Oncogene Protein p21(ras) / genetics metabolism Protein Multimerization Protein Structure, Secondary Signal Transduction raf Kinases / genetics metabolism
来 源:
DOI:10.1074/jbc.M113.537001
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